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Cases of amnesia
due to head injury provide clues about the anatomy of memory. Retrograde
amnesia occurs when a person loses memories for events that occurred prior to
the injury, while anterograde amnesia occurs when a person loses memories for
events that occur after the injury. The well known case of H.M., who
experienced anterograde amnesia, as well as subsequent research, points
toward the entire hippocampal region, as well as the parahippocampal region,
as a critical structure in many types of long-term memory. Many theorists
believe that the hippocampal region plays a key role in the consolidation of
memories – the hypothetical process involving the gradual conversion of
information into durable memory codes stored in long-term memory. This process
is complex, and many brain structures have been shown to be important in
memory.
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From a neural
perspective, memories appear to depend on localized neural circuits in the
brain. These are reusable pathways in the brain that may be specific for
specific memories. Various other lines of research have implicated
biochemical processes in the operation of memory. Studies show that
alterations in neurotransmitter secretions at specific synapse sites,
hormonal fluctuations, and protein synthesis in the brain are all related to
memory.
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In summary,
anatomical, neural, and biochemical processes all appear to play a role in
memory.
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