Fundamentals of Biology: Lecture Outline
Chapter 8 - How cells release stored energy
Cellular Respiration
- aerobic
- anaerobic
Aerobic Respiration
Summary Equation:
glucose + oxygen -----> carbon dioxide + water
3 series of Reactions:
Glycolysis
- enzymes in
At the end of glycolysis you have:
- two 3 carbon pyruvates
- net gain of
Preparatory Steps
- pyruvate enters mitochondrion
- is converted to
- gives off
- gives up hydrogens and electrons
Kreb's Cycle
- acetyl-CoA joins oxaloacetate
- forms 6 carbon
- cycle occurs twice
- 3 carbons enter
- 3 carbons leave
Functions of the cycle:
- transfer hydrogen ions and electrons
- produce
- rearrange intermediates into
Summary of Coenzymes Produced:
Glycolysis
Pyruvate conversion
Kreb's Cycle
TOTALS
Electron Transport Phosphorylation
Chemiosmotic Model of ATP production
- drives formation of
How do we get 36 ATP out of all this?
- 4 ATP form directly from
- 32 ATP form in E.T.P.
- for every NADH
- for every FADH2
In cells - 36 ATP
In heart, liver and kidney cells - 38 ATP
- difference is ATP yield from NADH formed in glycolysis
Anaerobic Routes
1. Lactate Fermentation
NET YIELD =
2. Alcoholic Fermentation (in yeast)
NET YIELD
3. Anaerobic Electron Transport
Alternative sources of energy:
- excess glucose intake is stored as:
Energy storage:
- 1%
- 78%
- 21%
Energy from fats:
Energy from proteins:
Review
Review questions 1-7
Self quiz 1-9