Temperature Regulation
1. Temperature and Metabolism
A. Effects of increased Temp
i. denaturation of
proteins
ii. thermal inactivation
iii. O2 solubility
iv. membrane fluidity
v. alterations in
enyzmatic rates
vi. Q10
B. Effects of decreased Temp
i. crystal formation
with freezing
a. "antifreezes", eg. glycerol, increased salts
C. Two classes of animals
i. homeotherms - maintain
internal temperature with changing environmental temp
ii. poikilotherms - internal
temperature varies with external temperature
2. Heat loss vs Heat gain
A. radiation
B. conduction
C. convection
D. evaporation
E. metabolic heat
3. Homeotherms
A. thermoneutral zone
i. no change in BMR
ii. vasoconstriction/vasodilation
B. lower critical temperature
i. increase in BMR
ii. shivering
iii. non-shivering thermogenesis
iv. voluntary muscle contraction
C. upper critical temperature
i. increase in BMR
ii. sweating
iii. panting
D. Monitoring body temperature
i. hypothalamus
a. set point
b. change in ANS, etc. to alter body temp
ii. peripheral receptors
4. Unique adapations
A. Marine mammals
i. blubber (insulation) - changes
in blood flow
ii. circulation in fins
a.
counter current heat exchanger
B. "Warm bodied Fishes"
i. poikilotherms
ii. local control of temperature
in fast muscles
iii. counter current heat exchanger